A mass of fibrous tissue containing hemosiderin-pigmented
macrophages and multinucleated giant cells, replacing and expanding
part of a bone in primary hyperparathyroidism.
Primary hyperparathyroidism, hyperparathyroidism due to neoplasms or
idiopathic hyperplasia of the parathyroid glands.
They appear as single or multiple, well defined lesions,
commonly affecting the facial bones, pelvis, ribs and femora. With
treatment. Brown tumours may demonstrate healing with increased
Para thyroid glands, two small paired endocrine glands, superior and
inferior, usually found embedded in the connective tissue capsule on
the posterior surface of the thyroid gland; they secrete parathyroid
hormone that regulates the metabolism of calcium and phosphorus.
Contrary to a name that suggests otherwise, brown tumors are a
nonneoplastic process. On radiographic evaluation their multifocal
involvement may be misconstrued as metastatic disease; however, the
clinical history of renal failure and secondary hyperparathyroidism
(or primary hyperparathyroidism) usually establishes the diagnosis.
Brown tumors are known to occur only in the setting of
hyperparathyroidism, and they rarely affect the spinal column.
Treatment of primary hyperparathyroidsm usually involves performing
a total or subtotal parathyroidectomy, and then stabilisation of the
lesion if mechanical damage has occured.
Brown tumour of nasal structures
Image 2 Brown Tumour of the spine MRI