Cysticercosis

 


Definition
Disease caused by encystment of cysticercus larvae. (from pork tapeworm infection)
 
Radiographic Appearance
The classic findings are multiple elongated foci of calcification just about the shape and size of grains of rice. These "rice grain" calcifications are usually oriented along the direction of the muscle fibers. It may also occur in the brain.
 
Pathology
What is cysticercosis?

Cysticercosis is an infection caused by the pork tapeworm, Taenia solium. Infection occurs when the tapeworm larvae enter the body and form cysticerci (SIS-tuh-sir-KEY) (cysts). When cysticerci are found in the brain, the condition is called neurocysticercosis (NEW-row SIS-tuh-sir-KO-sis).

Where is cysticercosis found?
The tapeworm that causes cysticercosis is found worldwide. Infection is found most often in rural, developing countries with poor hygiene where pigs are allowed to roam freely and eat human feces. This allows the tapeworm infection to be completed and the cycle to continue. Infection can occur, though rarely, if you have never traveled outside of the United States. Taeniasis and cysticercosis are very rare in Muslim countries where eating pork is forbidden.

How can I get cysticercosis?
By accidentally swallowing pork tapeworm eggs. Tapeworm eggs are passed in the bowel movement of a person who is infected. These tapeworm eggs are spread through food, water, or surfaces contaminated with feces. This can happen by drinking contaminated water or food, or by putting contaminated fingers to your mouth. A person who has a tapeworm infection can reinfect themselves (autoinfection). Once inside the stomach, the tapeworm egg hatches, penetrates the intestine, travels through the bloodstream and may develop into cysticerci in the muscles, brain, or eyes.

What are the signs and symptoms of cysticercosis?
Signs and symptoms will depend on the location and number of cysticerci in your body.

Cysticerci in the muscles:

Cysticerci in the muscles generally do not cause symptoms. However, you may be able to feel lumps under your skin.

Cysticerci in the eyes:

Although rare, cysticerci may float in the eye and cause blurry or disturbed vision. Infection in the eyes may cause swelling or detachment of the retina.

Neurocysticercosis (cysticerci in the brain, spinal cord):

Symptoms of neurocysticercosis depend upon where and how many cysticerci (often called lesions) are found in the brain. Seizures, and headaches are the most common symptoms. However, confusion, lack of attention to people and surroundings, difficulty with balance, swelling of the brain (called hydrocephalus) may also occur. Death can occur suddenly with heavy infections.

How long will I be infected before symptoms begin?
Symptoms can occur months to years after infection, usually when the cysts are in the process of dying. When this happens, the brain can swell. The pressure caused by swelling is what causes most of the symptoms of neurocysticercosis. Most people with cysticerci in muscles won’t have symptoms of infection.

How is cysticercosis diagnosed?
Diagnosis can be difficult and may require several testing methods. Your health care provider will ask you about where you have traveled and your eating habits. Diagnosis of neurocysticercosis is usually made by MRI or CT brain scans. Blood tests are available to help diagnose an infection, but may not always be accurate. If surgery is necessary, confirmation of the diagnosis can be made by the laboratory.

 

Treatment:
Infections are generally treated with anti-parasitic drugs in combination with anti-imflammatory drugs. Surgery is sometimes necessary to treat cases in the eyes, cases that are not responsive to drug treatment, or to reduce brain edema (swelling). Not all cases of cysticercosis are treated.

 

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Useful Link: http://www.cdc.gov/ncidod/dpd/parasites/