Your doctor may describe DCIS as a very early form of
breast cancer. Some doctors call it a pre-cancerous
condition because it may go on to develop into an invasive
cancer if it is not treated. DCIS is becoming more
common. This is because it is being picked up on
mammograms when women are screened for breast cancer.
Remember - it is
confusing, but
invasive ductal breast cancer and DCIS are not the
same thing. In invasive ductal breast cancer, the cells
have broken out of the ducts and so can spread.
Treatment
In the past, the recommended treatment for DCIS was nearly
always mastectomy.
This cures virtually all cases of DCIS because all the
affected tissue is removed before an invasive cancer has a
chance to develop.
Now most centres remove only the area of DCIS, with a
border of healthy tissue around it. This is called
wide local excision or conservative surgery. The DCIS cells
are examined under a microscope, and if they are high
grade, your doctor will suggest
radiotherapy to the rest of the breast tissue. This
is to kill off any abnormal cells left behind. You may be
given
tamoxifen (a type of hormone therapy) to try to reduce
the risk of developing an invasive breast cancer in the
future. But doctors don't know yet exactly how much
help tamoxifen is in stopping DCIS from coming back. A
2003 trial suggests that it may not provide much extra
protection if you've already had radiotherapy. Your
specialist may still prescribe it for you if the DCIS
cells are likely to
respond to oestrogen.
If you wish to, you can choose to have a mastectomy. Some
women prefer to know that the DCIS is cured. You may be
advised to have a mastectomy because
- The area of the DCIS in your breast is large
- There are several areas of DCIS in your breast
- You have small breasts and too much of the breast is
affected by DCIS to make wide local excision possible
DCIS trials results
There have been clinical trials looking into the treatment
of DCIS. Trial results so far show that
- It is reasonable for some women to have just the
DCIS removed
- Some women will not need any more treatment than
that
- Other women should have radiotherapy after the DCIS
has been removed
A study that reported in 2003 suggests that women over
50 who have had radiotherapy for DCIS won't get any extra
benefit from taking tamoxifen. Another earlier trial
compared radiotherapy with no further treatment after
wide local excision to remove DCIS. They found that 4
years after surgery,
- With radiotherapy, 9 women out of every 100 had a
recurrence of DCIS or developed breast cancer
- With no further treatment 16 women out of every 100
had a recurrence of DCIS or developed breast cancer
So there is not all that much difference in the two
groups. Some women will be fine with no further treatment.
Others should have radiotherapy. Whether you have more
treatment or not is generally decided on the grade of the
DCIS cells.
Treatment and DCIS grade
There are now ways of classifying DCIS into
high grade (more aggressive) and
low grade (less aggressive). Doctors think that the
high grade is more likely to come back. So women with high
grade should probably have radiotherapy after surgery.
While women with low grade DCIS probably do not need
further treatment.
Unfortunately the grading of DCIS had not been worked out
when the trials were started. The trials need to be
repeated using the grading system to confirm that this is
the best way of treating DCIS.
Follow up
Whichever treatment you receive, you will have regular
follow up appointments to make sure any recurrence of DCIS
in the treated breast is picked up as quickly as possible.
You should be offered mammograms at least every 2 years.
If your DCIS does come back,