Freiberg's disease

 


Definition
Bilateral aseptic bone necrosis of the
2nd metatarsal head, Freiberg-Kohler type (II)]
Kohler's Disease II, Freiberg-Kohler (both sides)
 
Radiographic Appearance
Freiberg's disease is the only bone necrosis that is more often seen in girls than in boys.

Grade
II: partially detached osteochondral lesion
III: completely detached, non-displaced fragment
IV: detached and displaced fragment

There are 4 stages:
1. Initial stage with cartilaginous edema and joint effusion. The X-ray is still unnoticeable, in MRI bone marrow edema.

2. Condensation-density of bone structures in hypermineralization of necrotic bony trabecula. In the X-ray it is already seen, in MRI double-line sign.

3. Fragmentation with deformity of joint structures. Up until this stage, 2 or 3 years since begin of disease may have passed.



4. Repair with replacement of necrotic tissue with the new bone substance. Requirement: Revascularisation

 

An early diagnosis is possible , next to MRI, with the 3-phase skeletal szintigraphy. Avascular bone areas are known as so-called "cold-spots".

 

Pathology
Aseptic bone necrosis are seen in children along with cartilage ossification defects throughout growth or throughout increased exertion. A cause may be passing intraossic vascularization disturbances through a mycotic-embolic vessel obstruction, bland infections, trauma, vessel spasms, vegetative dysregulations or vessel trauma. Constitutional and alimentary factors seem to play a role as well. The infestation can be unilateral or bilateral.  
 
Treatment:
Conservative: decompression and increased circulation. bed rest, no sports, decompressing wraps, support insoles. Antiphlogistical, hyperemic and physical therapy. Prostaglandin analogs such as Ilomedin (Schering)
Surgical: Drilling to result in pressure decompression and increased revascularization. Nailing/Pinning, correction in Freiberg-Kohler as, for example, open-flap osteotomies in the later stages with pain and deformation.
 

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