Intussusception

 


Intussusception is invagination of a segment of intestine, called the intussusceptum, into a more distal bowel segment, known as the intussuscipiens. 90% of intussusceptions are ileocolic. 90% have no lead point. When a lead point is present, the most common cause is a Meckel's diverticulum. Other causes include: polyps, enteric duplication cysts, an inflamed appendix, or lymphoma. Most commonly occur in male infants less than 2 years old. Patients present with pain, vomiting, or blood per rectum. Intussusception will lead to obstruction and ischemia of bowel.
 

Causes of Intussusception
In infants, the causes of intussusception are unknown, although there are some theories about why it occurs. Because intussusception is seen most often in spring and fall, this seems to suggest a possible connection to the kinds of viruses that children catch during these seasons, including upper respiratory infections.

In some cases, intussusception may follow a recent bout of gastroenteritis (sometimes called stomach flu). Gastrointestinal infections may cause swelling of the infection-fighting lymph tissue that lines the intestine, which may pull one part of the intestine into the other. Intussusception is most common around the age that infants are being introduced to solid foods. It has been suggested that the introduction of new foods may also cause some swelling of the lymph tissue in the intestines, increasing the chance of developing an instussusception.

Recently, there has also been some investigation into the rotavirus vaccine and its possible connection to intussusception, although the number of reported cases of intussusception among babies who received the vaccine is quite small. According to the U.S. Centers for Disease Control and Prevention (CDC), it has not been established that the vaccine causes intussusception, but the CDC and the U.S. Food and Drug Administration have suspended the vaccine until they're able to gather more information. Babies who received the rotavirus vaccine before its suspension have no increased risk of developing intussusception now.

Usually when an adult or a child older than 3 develops an intussusception, it's often the result of enlarged lymph nodes, a tumor, or a polyp in the intestine.

Signs and Symptoms
Children with an intussusception have intense abdominal pain, which often begins so suddenly that it causes loud, anguished crying and causes the child to draw the knees up to the chest. The pain is usually intermittent, but recurs and becomes stronger. As the pain subsides, a child with an intussusception may stop crying and seem fine.

Other common symptoms include:

  • abdominal swelling or distension
  • passing stools (or poop) mixed with blood and mucus, known as currant jelly stool (60% percent of infants with an intussusception will pass currant jelly stool)
  • vomiting
  • vomiting up bile, a bitter-tasting fluid secreted by the liver that's often golden-brown to greenish in color
  • lethargy (i.e., drowziness or sluggishness)
  • shallow breathing
  • grunting

As the illness progresses, a child will become progressively weaker and may develop a fever and appear to go into shock. Symptoms of shock include lethargy, rapid heartbeat, weak pulse, low blood pressure, and rapid breathing.

Complications of Intussusception
If left untreated, intussusception can cause severe complications. Complications are directly related to the amount of time that passes from when the intussusception occurred until it's treated. Most infants who are treated within the first 24 hours recover completely from an intussusception with no problems. Further delay increases the risk of complication which include irreversible tissue damage, perforation of the bowel, infection, and death.


Radiologic Overview of the Diagnosis:

Approximately 50% of plain film radiographs of the abdomen are normal. Plain film findings include: an intraluminal convex filling defect in an air-filled loop of bowel or an abnormal bowel gas pattern with lateralization of the distal small bowel. If plain films cannot completely exclude intussusception or if clinical correlation is high, an ultrasound or an enema may be performed. On ultrasound, a target or doughnut sign is characteristic with a hypoechoic ring surrounding an echogenic center. Air (pneumatic) or contrast (hydrostatic) reduction enema may be performed for both diagnosis and therapy (if successful). If there is free flow of air or contrast into the termimal ileum, the exam is negative and terminated. However, if positive, an convex intraluminal filling defect will be seen, most commonly in the transverse colon. Constant pneumatic or hydrostatic pressure should be maintained to reduce the intussusception. Free flow of contrast or air into the terminal ileum indicates successful reduction. There is a 5-10% recurrence rate. Complication of enema reduction includes perforation (1:300 cases).

Key Points:

90% of intussusceptions are ileocolic. 90% have no lead point.
When an intussusception is encountered during an enema, a convex intraluminal filling defect is seen, usually in the transverse colon.
Contraindications to intussusception reduction include perforation or peritonitis Definition

 

Images

 

 

 

 

This abdominal X-ray shows an intestinal condition in which a loop of bowel has slipped into another section of bowel (intussusception), causing swelling, reduced blood flow, obstruction, and tissue damage. Intussusception requires emergency treatment (barium enema or surgery) to prevent intestinal tissue death (necrosis), intestinal perforation, peritonitis, and death

 

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